Results 51 to 60 of about 91,047 (284)

Animal-assisted therapy

open access: yesNursing Management, 2013
Ranger, the cardiac Pet Therapy standard poodle, was called upon by a family member to visit Mrs. M, a patient hospitalized for worsening heart failure. Although short of breath, Mrs. M started talking to Ranger as he rested quietly on the bed beside her.
openaire   +4 more sources

The effect of animal-assisted therapy on fine motor skill development. [PDF]

open access: yesThe Young Researcher, 2020
This study investigated the effect of weekly animal assisted activities utilizing guinea pigs on the fine motor development of children in grades kindergarten through third while also aiming to find more engaging and effective methods of occupational ...
McWatters, M.
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Dog-Assisted Therapy in Mental Health Care: A Qualitative Study on the Experiences of Patients with Intellectual Disabilities

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
(1) Background: Dog-assisted therapy (DAT) is an experiential intervention to promote psychological, physical, and social functioning in children and adults.
Anke van Schooten   +4 more
doaj   +1 more source

Effects of equine-assisted interventions on older adults’ health: A systematic review

open access: yesInternational Journal of Nursing Sciences, 2022
Objective: Equine-assisted interventions (EAI) can improve a variety of health problems in older adults and thus promote their well-being. This systematic review aimed to synthesize studies on EAI to understand better their effects on the health of older
Léa Badin   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Current Status of Animal-Assisted Interventions in Scientific Literature: A Critical Comment on Their Internal Validity

open access: yesAnimals, 2020
Many meta-analyses and systematic reviews have tried to assess the efficacy of animal-assisted interventions (AAIs), reaching inconsistent conclusions.
Javier López-Cepero
doaj   +1 more source

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