Results 71 to 80 of about 4,857,461 (280)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Frontiers in PsychologyThis review deals with the questions why humans want to live with other animals and how this is at all possible. In fact, it has become common sense that living and working with companion animals entails major benefits for human wellbeing and health ...
Kurt Kotrschal
doaj +1 more source
Frontiers in Psychology, 2020 ObjectiveThe rationale of this study was to evaluate the efficacy of dog-assisted therapy (DAT) combined with pharmacological treatment in children and adolescents with fetal alcohol spectrum disorder (FASD).MethodWe conducted a randomized, rater-blinded,
Raquel Vidal +17 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Frontiers in Veterinary ScienceThe welfare of dogs and horses involved in animal-assisted services (AAS) has received increasing scholarly attention, reflecting growing recognition of the ethical complexity of human-animal interactions in these settings.
Friederike Zenker +3 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Animal-assisted therapy in health-care facilities [PDF]
How does the use of animal-assisted therapy compared to the lack of animal-assisted therapy affect the psychological well being of all ...
Milazzo, Haley +2 more
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Animal-assisted therapy : viewed from the animals perspective [PDF]
, 2009 Animal-assisted therapy had its large breakthrough in the 1960-ties when a psychiatrist named Boris Levinson discovered the great advantages of involving animals in the treatment of patients.
Svensson, Regina
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