Results 91 to 100 of about 91,047 (284)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Animal-assisted therapy in health-care facilities [PDF]
How does the use of animal-assisted therapy compared to the lack of animal-assisted therapy affect the psychological well being of all ...
Milazzo, Haley +2 more
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Effectiveness of Animal-Assisted Therapy: Therapists’ Perspectives
, 2013 Animal-assisted therapy has frequently been used with children who have autism spectrum disorder. This study examined animal-assisted therapists’ perceptions of effectiveness of animal-assisted therapy with children who have DSM-IV mental health ...
Budahn, Nichole M.
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Animal-Assisted Therapy: Motives and Rewards
, 2014 Animal-assisted therapy is a complimentary therapy utilized in health care to provide goal-directed therapy using dogs. The purpose of this study was to understand what motivates individuals to being animal-assisted volunteering and rewards that ...
Collins, Kailee Victoria
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Human animal interaction, animal assisted therapy and pet ownership in neurorehabilitation
Advances in Clinical Neuroscience & Rehabilitation, 2020 Edwards, Laura
doaj +1 more source
The biomechanics of negative-pressure wound therapy
, 2011 Includes references.Despite the success of negative-pressure wound therapy, its mechanism of action remains unclear. The common perception that it reduces tissue pressure and increases perfusion has recently been challenged following the observation that
Kairinos, Nicolas
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