Results 81 to 90 of about 237,946 (291)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The use of vacuum-assisted wound closure to enhance skin graft acceptance in a horse [PDF]

, 2011
A 16-year-old horse was admitted to the clinic of the Department of Surgery and Anesthesiology of Domestic Animals of the Faculty of Veterinary Medicine (Ghent University) for the treatment of a very large, non-healing wound extending over the ...
Jordana-Garcia, Mireia, Martens, Ann, Pint, Eva   +2 more
core  

The Physiological Mechanisms of Effect of Vitamins and Amino Acids on Tendon and Muscle Healing: A Systematic Review [PDF]

, 2018
© 2018 Human Kinetics, Inc.To evaluate the current literature via systematic review to ascertain whether amino acids/vitamins provide any influence on musculotendinous healing and if so, by which physiological mechanisms.
Abuja, Abuja, Akdemir, Akdemir, Anthony, Anthony, Anthony, Anthony, Anthony, Anthony, Anthony, Anthony, Arai, Arai, Barbul, Barbul, Blass, Blass, Bonci, Bonci, Bryant, Bryant, Buettner, Buettner, Cohen, Cohen, Collins, Collins, DerSimonian, DerSimonian, DiGuiseppi, DiGuiseppi, Dinçer, Dinçer, Ehrlich, Ehrlich, Ehrlich, Ehrlich, Eijnde, Eijnde, Ejaz, Ejaz, Galeano, Galeano, Gordon, Gordon, Gottrup, Gottrup, Greenwald, Greenwald, Gumina, Gumina, Hackam, Hackam, Hahn, Hahn, Henderson, Henderson, Hespel, Hespel, Hess, Hess, Higgins, Higgins, Hobson, Hobson, Holm, Holm, Hooijmans, Hooijmans, Hung, Hung, Hunt, Hunt, Judkins, Judkins, Kannus, Kannus, Kaplan, Kaplan, Kato, Kato, Kilkenny, Kilkenny, Kimball, Kimball, Kirk, Kirk, Knapik, Knapik, Knobloch, Knobloch, Li, Li, Li, Li, Lima, Lima, Malinauskas, Malinauskas, McDaniel, McDaniel, McGonigle, McGonigle, McHugh, McHugh, Moher, Moher, Moher, Moher, Molinero, Molinero, Mouw, Mouw, Negro, Negro, Norton, Norton, Notarnicola, Notarnicola, Otranto, Otranto, Pereira, Pereira, Pereira, Pereira, Petróczi, Petróczi, Petróczi, Petróczi, Petróczi, Petróczi, Popay, Popay, Raynaud-Simon, Raynaud-Simon, Reagan-Shaw, Reagan-Shaw, Rodgers, Rodgers, Rosa, Rosa, Sallis, Sallis, Sax, Sax, Schultz, Schultz, Sena, Sena, Sharp, Sharp, Shaw, Shaw, Shukla, Shukla, Stechmiller, Stechmiller, Stromberg, Stromberg, Sugaya, Sugaya, Svanberg, Svanberg, Tack, Tack, Tarnuzzer, Tarnuzzer, Tipton, Tipton, Torres-McGehee, Torres-McGehee, Tsilidis, Tsilidis, Uzgare, Uzgare, Vieira, Vieira, Vieira, Vieira, Viera, Viera, Virmani, Virmani, Wasserstein, Wasserstein, Watson, Watson, Wicke, Wicke, Williams, Williams, Woo, Woo, Yoshizawa, Yoshizawa, Ömeroğlu, Ömeroğlu   +197 more
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Pet Therapy Use in Pediatric Hospitals: an Internet Based Pilot Study [PDF]

, 2004
Introduction: In a technologically advanced health care system, health care providers continue to care for the physical, emotional, and spiritual well being of their patients.
Potter, Kara
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Treatment of necrotizing fasciitis using negative pressure wound therapy in a puppy [PDF]

, 2015
A two-month-old German shepherd dog was presented with anorexia, lethargy and left hind limb lameness associated with swelling of the thigh. Clinical findings combined with cytology led to the presumptive diagnosis of necrotizing fasciitis (NF ...
Abma, Eline, Bosmans, Tim, De Rooster, Hilde, Kitshoff, Adriaan, Stock, Emmelie, Vandenabeele, Sophie   +5 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Animal welfare in dog-assisted services: Perception of professionals in Germany

Human-Animal Interactions
Using a questionnaire and open questions, with the data compiled in SPSS and MS Excel, this study analyzes the perception, significance, and understanding of animal welfare in dogs in animal-assisted services from the perspective of animal-assisted ...
Katharina Ameli, Theresa F. Braun, Stephanie Krämer   +2 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source