Results 121 to 130 of about 891,962 (308)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Wishaw et al. (2024) Video S3

open access: yes
A capuchin named AP pulp fishes with a finger in Stemmadenia obovata fruit. AP makes a withdraw-to-eat movement associated with visual disengage, a blink and a lift of the mouth to a horizontal orientation of accept the food item from the finger with the
Animal Behavior & Cognition Journal (12484206)
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

I.Q. Zoo Guitar Duck

open access: yes, 1990
A coin deposited into the machine would cue the duck to push down on a lever on the amp, which turns on the guitar. Used in operant conditioning research, this item presented conditioned ducks performing for both enjoyment and education ...

core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Animal Behavior

open access: yes, 2001
xiii,543 hal,;ill,;34 ...
Alcock,John
core  

Wishaw et al. (2024) Video S2

open access: yes
A capuchin named MT makes an underhand touch-associated precision grasp. The target fruit Ficus ovalis is first touched and then the hand reverses movement direction in order to make a precision grasp of the item.Video S2 for: Whishaw, I.
Animal Behavior & Cognition Journal (12484206)
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Neural networks and animal behavior

open access: yes, 2005
DAL SITO DELL'EDITORE: How can we make better sense of animal behavior by using what we know about the brain? This is the first book that attempts to answer this important question by applying neural network theory. Scientists create Artificial Neural
GHIRLANDA, STEFANO, Enquist M.
core  

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