Results 111 to 120 of about 891,962 (308)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Food Pellet Dispensers -- Model KB-102 Feeders

open access: yes
Device used to dispense food as a form of reinforcement reward in animal training, where animals receive food when they perform a desired behavior. Soon after the trainers at Animal Behavior Enterprises (ABE) began training animals, they realized that ...

core  

Haslam (2024) Video S1

open access: yes
A group of wild European starlings making and using woolen tools. Most birds discard the tool after a single use, but one bird in the video repeatedly uses the same tool while adding to it from a nearby piece of fleece.Video S1 for: Haslam, M.
Animal Behavior & Cognition Journal (12484206)
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Human recognition of feline stress-related behavioral states from visual cues depends on observer characteristics

open access: yesScientific Reports
This study investigates humans’ ability to recognize cats’ stress-related behavioral states expressed through visual body language, including facial expressions, posture, and tail position.
Serenella d’Ingeo   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Animal Behavior Society Web Site

open access: yes
Established in 1964, the Animal Behavior Society (ABS) "is a non-profit scientific society, founded to encourage and promote the study of animal behavior." The four major sections of the ABS website include background information about the ...

core  

Differential Phoretic Vector Use Among Sympatric Caenorhabditis Nematodes and an Association With Invasive Nitidulid Beetles in Southwestern Germany

open access: yesEcology and Evolution
Little is known about the natural history of many Caenorhabditis nematodes, despite their relationship to the model species C. elegans. While these nematodes rely on invertebrate vectors to disperse to new habitats (phoresy), vector use for most species ...
Ryan Greenway   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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