Results 91 to 100 of about 891,962 (308)

Case Study of an Automatic Enrichment Device for Laying Hens on a Free-Range Laying Hen Farm

Agriculture, 2019
Access to adequate foraging material can reduce the occurrence of feather pecking and cannibalism in laying hens. Technical devices may help farmers provide enrichment material more effectively. However, research in this field is rare.
Melanie Schmidt, Jenny Stracke, Katja Kulke, Nicole Kemper, Birgit Spindler   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Animal Experiments: Conference Report

, 1986
Researchers who use animal subjects and representatives from the Royal Society for the Prevention of Cruelty to Animals and moderate antivivisection groups held a press seminar in London in June 1986.
Dawson, Jane
core  

How Do Perceptions of Zoo Animal Welfare Influence Public Attitudes, Experiences, and Behavioral Intentions? A Mixed-Methods Systematic Review [PDF]

The public expects zoos to provide high standards of animal care. Failing to meet public expectations can have detrimental impacts on public experiences and behavior, which in turn can compromise zoos’ organizational goals relative to conservation and ...
Beth Ventura, Laëtitia Maréchal, Jonathan Cooper, Nicki Phillips   +3 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures

BMC Biology
Background Social behavior and social organization have major influences on individual health and fitness. Yet, biomedical research focuses on studying a few genotypes under impoverished social conditions.
Caleb C. Vogt, Matthew N. Zipple, Daniel D. Sprockett, Caitlin H. Miller, Summer X. Hardy, Matthew K. Arthur, Adam M. Greenstein, Melanie S. Colvin, Lucie M. Michel, Andrew H. Moeller, Michael J. Sheehan   +10 more
doaj   +1 more source

Research Note: Differences in the pecking behavior of turkey hens in proximity to the feeding pan depending on their beak condition

Poultry Science
: The present study aimed to provide further insight on different pecking behavior of beak-trimmed and untrimmed turkey hens in proximity to the feeding pan.
Nina Volkmann, Janna Weidemann, Karolin Skiba, Pia Niewind, Nicole Kemper, Birgit Spindler   +5 more
doaj   +1 more source

Time Course Changes in the Blood Parameters and the Expression of Diencephalic CRH and AVT mRNA Due to Acute Isolation Stress in Chicks

The Journal of Poultry Science, 2011
It is important to quantify and estimate stressful stimulation because stress appears to limit productivity and welfare in poultry. The purpose of this study is to investigate the effect of acute isolation stress (5, 10 or 30min) on the levels of blood ...
Kouichi Yanagita, Jun-ichi Shiraishi, Shin-Ichi Kawakami, Takashi Bungo   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source