Results 81 to 90 of about 1,857,015 (284)

Low stress and safe handling of outdoor cattle - effective measures to improve work environment and avoid dangerous situations [PDF]

open access: yes, 2013
Grazing cattle are needed to preserve 450 000 hectares of semi-natural grasslands of high biodiversity in Sweden. Keeping cattle outdoors promotes their health and possibili¬ties to conduct natural behaviors.
Atkinson, S., Geng, Q., Salomon, E.
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

callsync: An R package for alignment and analysis of multi‐microphone animal recordings

open access: yesEcology and Evolution
To better understand how vocalisations are used during interactions of multiple individuals, studies are increasingly deploying on‐board devices with a microphone on each animal.
Simeon Q. Smeele   +4 more
doaj   +1 more source

Case Study of an Automatic Enrichment Device for Laying Hens on a Free-Range Laying Hen Farm

open access: yesAgriculture, 2019
Access to adequate foraging material can reduce the occurrence of feather pecking and cannibalism in laying hens. Technical devices may help farmers provide enrichment material more effectively. However, research in this field is rare.
Melanie Schmidt   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

animal2vec and MeerKAT: A self‐supervised transformer for rare‐event raw audio input and a large‐scale reference dataset for bioacoustics

open access: yesMethods in Ecology and Evolution
Bioacoustic research, vital for promoting conservation and understanding animal behaviour and ecology, faces a monumental challenge: analysing vast datasets where animal vocalizations are rare.
Julian C. Schäfer‐Zimmermann   +11 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Time Course Changes in the Blood Parameters and the Expression of Diencephalic CRH and AVT mRNA Due to Acute Isolation Stress in Chicks

open access: yesThe Journal of Poultry Science, 2011
It is important to quantify and estimate stressful stimulation because stress appears to limit productivity and welfare in poultry. The purpose of this study is to investigate the effect of acute isolation stress (5, 10 or 30min) on the levels of blood ...
Kouichi Yanagita   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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