Results 81 to 90 of about 8,267,355 (296)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Effects of Bile Acid Supplementation on Lactation Performance, Nutrient Intake, Antioxidative Status, and Serum Biochemistry in Mid-Lactation Dairy Cows

Animals
This experiment investigated the effects of different levels of bile acid (BA) additives in diets on the lactation performance, serum antioxidant metabolites, and serum biochemical indices of 60 multiparous mid-lactation dairy cows.
Yuhang Chen, Cong Yuan, Tianyu Yang, Han Song, Kang Zhan, Guoqi Zhao   +5 more
doaj   +1 more source

The European Federation of the Pharmaceutical Industry and Associations’ Research and Animal Welfare Group: Assessing and benchmarking ‘Culture of Care’ in the context of using animals for scientific purpose

Laboratory Animals. Journal of the Laboratory Animal Science Association, 2019
The European Federation of Pharmaceutical Industries and Associations’ Research and Animal Welfare group members reflected on the concept of a Culture of Care in relation to animal care and use and on differences in its understanding and application ...
Sally Robinson, Sue Sparrow, Bella Williams, T. Decelle, T. Bertelsen, Kirsty Reid, M. Chlebus   +6 more
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Effects of dietary carbohydrate composition on rumen fermentation characteristics and microbial population in vitro

Italian Journal of Animal Science, 2015
The objective of the experiment was to evaluate the effects of dietary carbohydrate composition on rumen fermentation characteristics and microbial populations in vitro. The treatments were organized in three different carbohydrate composition diets: the
Xiangfei Zhang, Haibo Zhang, Zhisheng Wang, Xiaoming Zhang, Huawei Zhou, Cui Tan, Quanhui Peng   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Nutritional Interventions Improved Rumen Functions and Promoted Compensatory Growth of Growth-Retarded Yaks as Revealed by Integrated Transcripts and Microbiome Analyses

Frontiers in Microbiology, 2019
Growth retardation reduces the incomes of livestock farming. However, effective nutritional interventions to promote compensatory growth and the mechanisms involving digestive tract microbiomes and transcripts have yet to be elucidated.
Rui Hu, Huawei Zou, Zhisheng Wang, Binghai Cao, Quanhui Peng, Xiaoping Jing, Yixin Wang, Yaqun Shao, Zhaoxi Pei, Xiangfei Zhang, Bai Xue, Lizhi Wang, Suonan Zhao, Yuqing Zhou, Xiangying Kong   +14 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Changes in the rumen development, rumen fermentation, and rumen microbiota community in weaned calves during steviol glycosides treatment

Frontiers in Microbiology
Early weaning leads to weaning stress in calves, which hinders healthy growth and development. As an excellent sweetener applied in food, steviol glycosides (STE) has also been shown to exhibit positive biological activity in monogastric animals ...
Kexin Wang, Maocheng Jiang, Yuhang Chen, Yuncheng Huang, Zhiqiang Cheng, Osmond Datsomor, Shakib Mohamed Jama, Liping Zhu, Yajing Li, Guoqi Zhao, Guoqi Zhao, Guoqi Zhao, Miao Lin   +12 more
doaj   +1 more source

Scaffold-based 3D cell culture models in cancer research

Journal of Biomedical Sciences
Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems.
Waad H. Abuwatfa, W. Pitt, G. Husseini
semanticscholar   +1 more source