Results 91 to 100 of about 1,350,044 (307)

REVIEW: ANIMAL SERUM REPLACEMENT IN MESENCHYMAL STEM CELLS CULTURE

, 2023
Mesenchymal stem cells (MSCs) are being used in clinical applications and must comply with Good Manufacturing Practices (GMP) standards and The National Agency of Drug and Food Control (NA-DFC)) regulations. MSCs cultured using a culture medium and added
Noviantari, Ariyani
core   +1 more source

Editorial: Songs and Signs: Interdisciplinary Perspectives on Cultural Transmission and Inheritance in Human and Nonhuman Animals

Frontiers in Psychology, 2022
Julia Hyland Bruno, Brian Boyd, David Rothenberg   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Animals in Surgery -- Surgery in Animals: Nature and Culture in Animal-Human Relationship and Modern Surgery

, 2009
AThis paper looks at the entangled histories of animal-human relationship and modem surgery. It starts with the various different roles animals have in surgery--patients, experimental models and organ providers--and analyses where these seemingly ...
Schlich, Thomas, Rock, Melanie, Mykhalovskiy, Eric   +2 more
core  

Animal culture research should include avian nest construction. [PDF]

Biol Lett, 2021
Breen AJ.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A deepening understanding of animal culture suggests lessons for conservation. [PDF]

Proc Biol Sci, 2021
Brakes P, Carroll EL, Dall SRX, Keith SA, McGregor PK, Mesnick SL, Noad MJ, Rendell L, Robbins MM, Rutz C, Thornton A, Whiten A, Whiting MJ, Aplin LM, Bearhop S, Ciucci P, Fishlock V, Ford JKB, Notarbartolo di Sciara G, Simmonds MP, Spina F, Wade PR, Whitehead H, Williams J, Garland EC.   +24 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Between animal research and animal welfare: Analysing the openness practices of UK Named Veterinary Surgeons

The use of animals as scientific models is argued to be crucial for producing new scientific and medical knowledge and clinical treatments. However, animal research continues to raise socio-ethical concerns.
Pru Hobson-West, McGlacken, Renelle, Renelle McGlacken, Hobson-West, Pru   +3 more
core   +1 more source