Results 91 to 100 of about 2,509,574 (361)

DYSREGULATION OF GASTROINTESTINAL RAGE (RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS) EXPRESSION IN A SPONTANEOUS ANIMAL MODEL OF INFLAMMATORY BOWEL DISEASE [PDF]

, 2021
Angela Isabel Cabrera-García, Martina Protschka, Stefanie Kather, Franziska Dengler, Gottfried Alber, Uwe Müller, Jöerg M. Steiner, Romy M. Heilmann   +7 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Effects of Deferasirox in Alzheimer’s Disease and Tauopathy Animal Models [PDF]

, 2022
Ping Kwan, Amy Ho, Larry Baum
openalex   +1 more source

Integrating socio-eco-epidemiological approaches into health research [PDF]

, 2012
Sixty percent of emerging infectious diseases events are zoonotic and among those, 72% are caused by pathogens of wildlife origin. The distribution and intensity of most animal and zoonotic diseases have changed in recent years in response to ...
Gaidet, Nicolas, Molia, Sophie
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Terminological field “animal diseases” in the English language

Studia Humanitatis, 2020
The paper characterises peculiarities of the terminological field “animal diseases” formation in the English language. According to the analysis the author traces the terminological field genesis and determines its main sources of replenishment in the ...
Rozhkov Yuriy Hryhorevych
doaj  

How Scary Are Food Scares? Evidence from Animal Disease Outbreaks [PDF]

, 2017
Dwight M. Houser, Berna Karali, Houser, Dwight M., Karali, Berna   +3 more
openalex   +1 more source

Developing a disease prevention strategy in the Caribbean: the importance of assessing animal health related risks at the regional level [PDF]

, 2012
In 2009, the Caribbean Animal Health Network (CaribVET) conducted a survey among Caribbean national Veterinary Services to assess perceptions towards the use of risk assessment (RA) by animal health services in the region and to identify the main exotic ...
Gongora, Victor, Guitian, Javier, Herbert-Hackshaw, K., Lefrançois, Thierry, Percedo Abreu, M.I., Pradel, Jennifer   +5 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source