Results 91 to 100 of about 1,305,748 (308)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Animal Diseases Caused by Orbiviruses, Algeria

open access: yesEmerging Infectious Diseases, 2011
Antibodies against bluetongue virus were detected in cattle, sheep, goats, and camels in Algeria in 2008. Antibodies against epizootic hemorrhagic disease virus were detected in cattle, but antibodies against African horse sickness virus were not ...
Hafsa Madani   +9 more
doaj   +1 more source

Editorial: Aquaculture animal diseases: pathogens and control. [PDF]

open access: yesFront Cell Infect Microbiol, 2023
Ma R, Yang Y, Cao H, Li P.
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Editorial: Proceedings of the 3rd ISESSAH Conference 2019

open access: yesFrontiers in Veterinary Science, 2021
Dustin L. Pendell   +5 more
doaj   +1 more source

Prevalence of Batrachochytrium dendrobatidis in Amphibians in Northwestern Italy’s Protected Areas

open access: yesAnimals
Chytridiomycosis, caused by the fungus Batrachochytrium dendrobatidis (Bd), is a significant threat to global amphibian populations, leading to widespread declines and extinctions.
Arianna Meletiadis   +7 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

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