Results 241 to 250 of about 2,509,574 (361)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Editorial: Predicting, managing, and minimizing mycotoxicosis in farm animals
Frontiers in Fungal BiologyJesús Adonai Maguey-González +3 more
doaj +1 more source
Assessing the impact of better control of livestock diseases in Africa [PDF]
, 2012 International Laboratory for Research on Animal Diseases
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Viral Infectious Diseases in Wild Animals in Japan
, 2012 Hiroshi Shimoda +3 more
openalex +1 more source
The carrier state in cattle infected with Theileria parva [PDF]
, 2012 International Laboratory for Research on Animal Diseases
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source