Results 61 to 70 of about 1,013,030 (266)

Engineered nanomaterials and crops: physiology and growth of barley as affected by nanoscale cerium oxide

open access: yesItalian Journal of Agronomy, 2016
In recent years, remarkable progress has been made in developing nanotechnology. This has led to a fast-growth of commercial applications, which involve the use of a great variety of manufactured nanomaterials.
Alessandro Mattiello   +9 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Particulate Matter (PM10) Concentrations and Emissions at a Commercial Laying Hen House with High-Quality and Long-Term Measurement

open access: yesAtmosphere
Particulate matter (PM) is a significant air pollutant in modern egg production. However, high-quality PM data from commercial egg farms are still very limited.
Ji-Qin Ni, Albert J. Heber
doaj   +1 more source

Animals, Sport, and the Environment [PDF]

open access: yes, 2020
Abstract To outline the multiple ways in which animals are inserted into sporting practices, outline historical and contemporary approaches to studying human–animal sporting practices, and advocate for the centering of sociological problems in human–animal research in sporting contexts and cultures and for considering such problems in
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Caracterização do microclima dos diferentes layouts de caixas no transporte de ovos férteis Characterization of microclimate in different layout of boxes during transport of fertile eggs

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2013
Quando as condições microclimáticas e de transporte são combinadas inadequadamente, os componentes dos ovos férteis podem ser danificados. Objetivou-se, com este trabalho, caracterizar e analisar a dependência espacial dos perfis microclimáticos no ...
Aérica C. Nazareno   +4 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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