Results 71 to 80 of about 1,013,030 (266)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Sustainable Livestock Development In The Border Of Merauke Region Based On Environment

open access: yesE3S Web of Conferences, 2018
The purpose of this research is to provide information on sustainable livestock strategies with regard to the environment and social of Papua local communities in the process of cattle breeding process. In addition to increasing the productivity of local
Muchlis Dirwan, Nurcholis
doaj   +1 more source

Catalytic pyrolysis of swine manure using CO2 and steel slag

open access: yesEnvironment International, 2019
Pyrolysis of swine manure (SM) was conducted as a case study to establish an environmentally sound management of livestock manure. To build a more renewable pyrolysis platform for SM, this study selected carbon dioxide (CO2) as the reaction medium.
Dong-Jun Lee   +10 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Single-node cuttings for budbreak phenotyping in grapevine [PDF]

open access: yesBIO Web of Conferences
Budbreak is a critical stagein terms of vulnerability tospring frost, a major issue accentuated by the advancement of grapevine development due to global warming. Recognizing the determinants of budbreak regulation is essential to allow the selection, or
De Rosa Valeria   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Effect of different bagging treatments on the fruit quality in Chuxialü pear [PDF]

open access: yesGuoshu xuebao
[Objective] The primary aim of this study was to elucidate the impact of fruit bagging on the quality of Chuxialü pear fruits, thereby providing a scientific basis for achieving high-quality production of this pear variety.
YE Yanhui   +7 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy