LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
From here to Utopia: Theories of Change in Nonideal Animal Ethics. [PDF]
J Agric Environ Ethics, 2022 Müller ND.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Putting the Questions First-Flipped Classroom Methods in Animal Ethics Online Teaching and Its Evaluation. [PDF]
Animals (Basel), 2023 Dieck K, Grimm H.
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Dogs detect the virus: understanding Christian animal ethics vis-à-vis screening method for COVID-19 in humans. [PDF]
J Public Health (Oxf), 2022 Cordero DA.
europepmc +1 more source
Environmental Ethics, Animal Welfarism, and the Problem of Predation: A Bambi Lover's Respect For Nature [PDF]
, 2001 Jennifer Everett
openalex +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Applied Animal Ethics in Industrial Food Animal Production: Exploring the Role of the Veterinarian. [PDF]
Animals (Basel), 2022 Hernandez E, Llonch P, Turner PV.
europepmc +1 more source
Ranking of Production Animal Welfare and Ethics Issues in Australia and New Zealand by Veterinary Students [PDF]
, 2018 Amelia Cornish +11 more
openalex +1 more source