Results 11 to 20 of about 11,296,990 (297)

What is the optimum design for my animal experiment? [PDF]

open access: yesBMJ Open Sci, 2021
Within preclinical research, attention has focused on experimental design and how current practices can lead to poor reproducibility. There are numerous decision points when designing experiments. Ethically, when working with animals we need to conduct a
Karp NA, Fry D.
europepmc   +2 more sources

Feasibility and Safety of Dual-console Telesurgery with the KangDuo Surgical Robot-01 System Using Fifth-generation and Wired Networks: An Animal Experiment and Clinical Study. [PDF]

open access: yesEur Urol Open Sci, 2023
The coronavirus disease 2019 pandemic has drawn attention to telesurgery. Important advances in fifth-generation (5G) mobile telecommunication technology have facilitated the rapid evolution of telesurgery.
Fan S   +9 more
europepmc   +2 more sources

Network pharmacology analysis and animal experiment validation of neuroinflammation inhibition by total ginsenoside in treating CSM.

open access: yesPhytomedicine, 2023
BACKGROUND Cervical spondylotic myelopathy (CSM) is a degenerative pathology that affects both upper and lower extremity mobility and sensory function, causing significant pressure on patients and society.
Zhuo-Yao Li   +11 more
semanticscholar   +1 more source

A long-term animal experiment indicating persistent infection of bovine coronavirus in cattle. [PDF]

open access: yesJ Vet Med Sci, 2018
A long-term animal experiment involving inoculation with bovine coronavirus (BCoV) was conducted to verify its persistent infection in cattle. Three colostrum-deprived Holstein calves were housed separately in individual rooms of a high-containment ...
Kanno T, Ishihara R, Hatama S, Uchida I.
europepmc   +2 more sources

Application of Organoid Models in Prostate Cancer Research

open access: yesFrontiers in Oncology, 2021
Complex heterogeneity is an important characteristic in the development of prostate cancer (PCa), which further leads to the failure of known therapeutic options.
Ligui Zhou   +4 more
doaj   +1 more source

Modified Baihu decoction therapeutically remodels gut microbiota to inhibit acute gouty arthritis

open access: yesFrontiers in Physiology, 2022
Background: Acute gouty arthritis (AGA) is the most common first symptom of gout, and the development of gout as a metabolic and immune inflammatory disease is also correlated with the gut microbiota.
Xianyang Wang   +7 more
doaj   +1 more source

Forgotten forbs: Standard vegetation surveys underrepresent ecologically and culturally important forbs in a threatened grassland ecosystem

open access: yesConservation Science and Practice, 2022
Forbs are a culturally and ecologically important yet poorly studied component of the Pacific Northwest Bunchgrass (PNB) ecosystem of western North America.
Bryan A. Endress   +3 more
doaj   +1 more source

Impulse for animal welfare outside the experiment

open access: yesLaboratory Animals. Journal of the Laboratory Animal Science Association, 2020
Animal welfare is a growing societal concern and the well-being of animals used for experimental purposes is under particular scrutiny. The vast majority of laboratory animals are mice living in small cages that do not offer very much variety.
L. Lewejohann   +3 more
semanticscholar   +1 more source

Proteomic profiling of the human amniotic stem cell-highly abundant secreted proteins [PDF]

open access: yesPeerJ
Amnion-derived stem cells exhibit several significant advantages, including low immunogenicity, anti-inflammatory, anti-fibrotic, and angiogenic properties, which have garnered considerable attention as a potential source for cell therapy.
Dan He   +6 more
doaj   +2 more sources

A PDX model combined with CD-DST assay to evaluate the antitumor properties of KRpep-2d and oxaliplatin in KRAS (G12D) mutant colorectal cancer

open access: yesHeliyon, 2022
Patient-derived xenograft (PDX) models are more faithful in maintaining the characteristics of human tumors than cell lines and are widely used in drug development, although they have some disadvantages, including their relative low success rate, long ...
Wuguo Li   +13 more
doaj   +1 more source

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