Results 21 to 30 of about 4,974,799 (302)

Biosafety and data quality considerations for animal experiments with highly infectious agents at ABSL-3 facilities

Journal of Biosafety and Biosecurity, 2019
Animal models are crucial for the study of severe infectious diseases, which is essential for determining their pathogenesis and the development of vaccines and drugs.
Ming Guo, Yong Wang, Jinbiao Liu, Zhixiang Huang, Xiangdong Li   +4 more
doaj   +1 more source

Application of Organoid Models in Prostate Cancer Research

Frontiers in Oncology, 2021
Complex heterogeneity is an important characteristic in the development of prostate cancer (PCa), which further leads to the failure of known therapeutic options.
Ligui Zhou, Ligui Zhou, Caiqin Zhang, Yongbin Zhang, Changhong Shi   +4 more
doaj   +1 more source

Modified Baihu decoction therapeutically remodels gut microbiota to inhibit acute gouty arthritis

Frontiers in Physiology, 2022
Background: Acute gouty arthritis (AGA) is the most common first symptom of gout, and the development of gout as a metabolic and immune inflammatory disease is also correlated with the gut microbiota.
Xianyang Wang, Haishan Long, Ming Chen, Zongbo Zhou, Qinlin Wu, Shijie Xu, Geng Li, Zhifu Lu   +7 more
doaj   +1 more source

Forgotten forbs: Standard vegetation surveys underrepresent ecologically and culturally important forbs in a threatened grassland ecosystem

Conservation Science and Practice, 2022
Forbs are a culturally and ecologically important yet poorly studied component of the Pacific Northwest Bunchgrass (PNB) ecosystem of western North America.
Bryan A. Endress, Joshua P. Averett, Shawn Steinmetz, Eric J. Quaempts   +3 more
doaj   +1 more source

Proteomic profiling of the human amniotic stem cell-highly abundant secreted proteins [PDF]

PeerJ
Amnion-derived stem cells exhibit several significant advantages, including low immunogenicity, anti-inflammatory, anti-fibrotic, and angiogenic properties, which have garnered considerable attention as a potential source for cell therapy.
Dan He, Yuqiang Cheng, Hongkai Lv, Anqi Geng, Jie Zheng, Lin Dang, Pengfei Li   +6 more
doaj   +2 more sources

A PDX model combined with CD-DST assay to evaluate the antitumor properties of KRpep-2d and oxaliplatin in KRAS (G12D) mutant colorectal cancer

Heliyon, 2022
Patient-derived xenograft (PDX) models are more faithful in maintaining the characteristics of human tumors than cell lines and are widely used in drug development, although they have some disadvantages, including their relative low success rate, long ...
Wuguo Li, Wei Chen, Jialin Wang, Guangyin Zhao, Lianzhou Chen, Yong Wan, Qianxin Luo, Wenwen Li, Haoji Huang, Wenying Li, Wu Li, Yutong Yang, Daici Chen, Qiao Su   +13 more
doaj   +1 more source

Recombinant adenovirus expressing vesicular stomatitis virus G proteins induce both humoral and cell-mediated immune responses in mice and goats

BMC Veterinary Research, 2021
Background Vesicular stomatitis (VS) is an acute, highly contagious and economically important zoonotic disease caused by the vesicular stomatitis virus (VSV).
Xiaojuan Xue, Zhaorong Yu, Hongyan Jin, Lin Liang, Jiayang Li, Xiaolu Li, Yong Wang, Shangjin Cui, Gang Li   +8 more
doaj   +1 more source

Effects of human-animal relationship on animal productivity and welfare [PDF]

, 2020
This is a literature review of the effects of humans´ relationships with farm animals on animal productivity and welfare, including the following topics: definition of the concept and description of different tests that have been developed to measure ...
Alonso-Spilsbury, María, Maurice Broom, Donald, Velarde, Antonio, Mota-Rojas, Daniel, Napolitano, Fabio, Orihuela, Agustín   +5 more
core   +1 more source

Modulatory Effects of Probiotics During Pathogenic Infections With Emphasis on Immune Regulation

Frontiers in Immunology, 2021
In order to inhibit pathogenic complications and to enhance animal and poultry growth, antibiotics have been extensively used for many years. Antibiotics applications not only affect target pathogens but also intestinal beneficially microbes, inducing ...
Abdul Raheem, Abdul Raheem, Lin Liang, Lin Liang, Guangzhi Zhang, Guangzhi Zhang, Shangjin Cui, Shangjin Cui   +7 more
doaj   +1 more source

Genome Characterization and Phylogenetic Analysis of the First Bovine Rhinitis B Virus Isolate in China

Frontiers in Veterinary Science, 2021
Bovine rhinitis B virus (BRBV) is an emerging viral species in the genus Aphthovirus, family Picornaviridae. Studies suggested that BRBV was considered a potential etiological agent of bovine respiratory disease complex (BRDC).
Shao-Lun Zhai, Yi-Lun Xie, Qi Zhai, Xiao-Hui Wen, Dian-Hong Lv, Qin-Ling Chen, Gang Wang, Wen-Kang Wei, Wen-Kang Wei   +8 more
doaj   +1 more source