Results 171 to 180 of about 377,815 (340)

Antivivisection, The Law, and Animal Experimentation [PDF]

, 1966
O\u27Connell, Daniel C., Morandi, Anthony J., Onuska, Linda A.   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Animal Experimentation [PDF]

Science, 1932
openaire   +2 more sources

Mechanistic insights into the anti-depressant effect of quercetin: an integrated bibliometrics, bioinformatics, and animal experimentation. [PDF]

Front Nutr
Song Z, Wu Y, Luo L, Hu Q, Wu S, Wu M, Zhang G.   +6 more
europepmc   +1 more source

The ethical governance of German physicians 1890-1939: are there lessons from history? [PDF]

, 2011
Dingwall, R, Rozelle, V
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Conceptual foundations for a clarified meaning of the 3Rs principles in animal experimentation. [PDF]

Anim Welf
Louis-Maerten E, Rodriguez Perez C, Cajiga RM, Persson K, Elger BS.   +4 more
europepmc   +1 more source

חופש המידע נגד חופש ההסתרה, חופש הביטוי נגד חופש העינוי: ניסויים בבעלי חיים מאחורי דלתות המעבדה Freedom of Information vs. Freedom of Concealment, Freedom of Speech vs. Freedom of Torture: Animal Experimentation behind the Laboratory Doors

, 2018
Asaf Harduf
openalex   +1 more source

Animal Experimentation: Oh, when will they ever learn? [PDF]

, 2016
Michael Balls
openalex   +1 more source

Supp. Info. and Data for Forensic analysis of novel SARS2r-CoV identified in game animal datasets in China shows evolutionary relationship to Pangolin GX CoV clade and apparent genetic experimentation

, 2022
Adrian Jones, Steven E. Massey, Daoyu Zhang, Yuri Deigin, Steven C. Quay   +4 more
openalex   +1 more source