Results 31 to 40 of about 2,045,746 (251)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

White-tailed deer response to vehicle approach: evidence of unclear and present danger. [PDF]

open access: yesPLoS ONE, 2014
The fundamental causes of animal-vehicle collisions are unclear, particularly at the level of animal detection of approaching vehicles and decision-making. Deer-vehicle collisions (DVCs) are especially costly in terms of animal mortality, property damage,
Bradley F Blackwell   +2 more
doaj   +1 more source

Flight tests of a digital data acquisition system for analysis of ultrasonic pulse-echo signals used to measure ice accretion [PDF]

open access: yes, 1986
May 1986Also issued as an M.S. thesis, Massachusetts Institute of Technology. Dept. of Aeronautics and Astronautics, 1986Includes bibliographical references (p.
Ryan, Justin Mark, Hansman, Robert John.
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Application of the calculus of variations in determining optimum flight profiles for commercial short haul aircraft [PDF]

open access: yes, 1966
December 1966Includes bibliographical references (p. 52-53)The method of steepest descent of the calculus of variations is used to determine the optimal flight profile of a hypothetical tilt wing aircraft travelling a distance of 50 miles.
Gallant, Robert Alfred
core  

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Sex-related interannual plasticity in wing morphological design in Heliconius charithonia enhances flight metabolic performance.

open access: yesPLoS ONE, 2020
Flight morphological variations and its consequences on animal performance are common in winged insects. In the butterfly Heliconius charithonia, sex-related differences in the wing morphological design have been described resulting in differences in ...
Velia I Ramos-Pérez   +4 more
doaj   +1 more source

Adaptive Bird-like Genome Miniaturization During the Evolution of Scallop Swimming Lifestyle

open access: yesGenomics, Proteomics & Bioinformatics, 2022
Genome miniaturization drives key evolutionary innovations of adaptive traits in vertebrates, such as the flight evolution of birds. However, whether similar evolutionary processes exist in invertebrates remains poorly understood. Derived from the second-
Yuli Li   +10 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

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