Results 211 to 220 of about 2,326,634 (293)

Genome-wide SNP-based genomic diversity and population structure analysis in alpaca populations from Europe and Peru. [PDF]

G3 (Bethesda)
Tan K, Adeniyi OO, Letko A, Manz E, Wagner HW, Zanolari P, More M, Gutierrez-Reynoso GA, Drögemüller C, Lühken G.   +9 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Research Trends and Emerging Frontiers in Racehorse Genetics: A Bibliometric Analysis. [PDF]

Animals (Basel)
Huang Q, Yao X, Yang X, Wang T, Li X, Shan D, Su Y, Wang J.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Developing a strain-dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context. [PDF]

Animal Model Exp Med
Zohud O, Nashef A, Abu-Elnaaj I, Iraqi FA.   +3 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Correction to "Additional Evidence Fails to Associate Variation in KCNE4 With Equine Anhidrosis". [PDF]

Anim Genet
europepmc   +1 more source

Editorial: Nutrigenetics and nutrigenomics in livestock. [PDF]

Front Genet
Polizel GHG, Diniz WJS, Brito LF, Santana MHA.   +3 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A Large-Scale Cross-Population Evaluation of Genetic Risk Variants for Dilated Cardiomyopathy in Dobermanns. [PDF]

Anim Genet
Hulsman AH, Flokstra G, Kijan C, van Rumpt M, Vernooij JCM, Nelson TC, Liu S, Vree L, Harakalova M, Ljungvall I, Haggstrom J, Wess G, Fieten H, Hytönen MK, Lohi H, van Steenbeek FG.   +15 more
europepmc   +1 more source