Results 101 to 110 of about 11,419,560 (364)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Impact of climate change on animal health and welfare

Animal Frontiers, 2018
Climate is one of many factors with the potential to alter disease states and is expected to exert an overwhelming negative effect on the health of humans and animals (Rabinowitz and Conti, 2013).
N. Lacetera
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Guidance on Good Practice in Conducting Scientific Assessments in Animal Health using Modelling

EFSA Journal, 2009
The European Food Safety Authority (EFSA) asked the Panel on Animal Health and Welfare to develop a guidance document on Good Practice in Conducting Scientific Assessments in animal health using modelling.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Scientific Opinion on Hatchery Waste as animal by‐products

EFSA Journal, 2011
The risk posed by the possible use of dead‐in‐shell chicks for the production of processed petfood was assessed. According to current legislation two processing methods were considered i) treatment to a minimum Fc value of 3; and ii) treatment of at ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Risks to human and animal health related to the presence of deoxynivalenol and its acetylated and modified forms in food and feed

EFSA journal. European Food Safety Authority, 2017
Deoxynivalenol (DON) is a mycotoxin primarily produced by Fusarium fungi, occurring predominantly in cereal grains. Following the request of the European Commission, the CONTAM Panel assessed the risk to animal and human health related to DON, 3‐acetyl ...
H. Knutsen, J. Alexander, L. Barregard, M. Bignami, B. Brüschweiler, S. Ceccatelli, B. Cottrill, M. Dinovi, B. Grasl-Kraupp, C. Hogstrand, L. Hoogenboom, C. Nebbia, I. Oswald, A. Petersen, M. Rose, A. Roudot, T. Schwerdtle, C. Vleminckx, G. Vollmer, Heather M. Wallace, S. de Saeger, G. Eriksen, P. Farmer, J. Frémy, Y. Gong, K. Meyer, H. Naegeli, D. Parent-Massin, I. Rietjens, H. V. van Egmond, A. Altieri, M. Eskola, P. Gergelová, Luisa Ramos Bordajandi, B. Benkova, B. Dörr, A. Gkrillas, Nicklas Gustavsson, Mathijs van Manen, L. Edler   +39 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source