Results 121 to 130 of about 3,677,147 (314)
Evaluation of animal welfare on organic dairy farms in Finland [PDF]
, 2000 The evaluation of animal welfare on organic dairy farms was carried out in connection with the first Finnish research study on animal healthcare and welfare in 1996 to 1998.
Roiha, Ulla
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Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Development of an advisory system that supports good animal welfare in organic production in Norway [PDF]
, 2004 Organic agriculture wishes to emphasise animal welfare, and aims to be at the forefront with regard to promoting the welfare of farm animals. It is therefore important to increase the expertise in the field of animal welfare in organic farming systems ...
Henriksen, Britt I. F.
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Communication in animal health and welfare planning [PDF]
, 2008 The project ‘Minimising medicine use in organic dairy herds through animal health and welfare promotion’ is focused on animal welfare assessment and its role in the active use of animal health plans in order to improve animal health and welfare on ...
Smolders, Gidi +2 more
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Characterisation of small ruminant production in Crete [PDF]
, 2011 Subproject 2 of the LowInputBreeds project aims to improve performance, animal health & welfare, and product quality in organic and low input breed sheep production systems.
Smaragda, Sotiraki +1 more
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