Results 131 to 140 of about 2,468,439 (322)
Whatever happened to meaning? Commentary on Millikan: A common structure for concepts of individuals, stuffs, and real kinds [PDF]
, 1998 Even in infancy, concept formation has to do with creating meaning, not with tracking substances. Preverbal infants can identify a substance such as a dog, but their first concept of this substance is not dog but animal.
Mandler, JM
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
JDS CommunicationsVideo-based livestock monitoring offers a noninvasive, cost-effective, and scalable alternative to direct human monitoring, but also to commonly used collar or ear tag devices on farms.
Anne-Cécile Toulemonde +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Identify and Report Water Pollution: An Interpretive Guide to Surface Water Conditions of the New Hampshire Coastal Watershed, 2nd edition [PDF]
, 2007 This gude was designed to help people who work or recreate outdoors to interpret surface water conditions so that they would recognize a pollution incident and know how to report it.
New Hampshire Estuaries Project
core +4 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Threats to soil quality in Denmark - A review of existing knowledge in the context of the EU Soil Thematic Strategy [PDF]
, 2009 The EU Commission is preparing a proposal for a Soil Framework Directive with the purpose of protecting the soil resources in Europe. The proposal identifies six major threats to the sustained quality of soils in Europe. This report addresses the threats
Christensen, B.T. +2 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Florida marine biotechnology: research, development and training capabilities to advance science and commerce [PDF]
, 2001 The level of activity and interest in “marine biotechnology” among Florida university faculty and allied laboratory scientists is reported in this document.
Seaman, William +1 more
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