Results 121 to 130 of about 521,393 (302)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Forecasting spring from afar? Timing of migration and predictability of phenology along different migration routes of an avian herbivore

, 2015
1.Herbivorous birds are hypothesized to migrate in spring along a seasonal gradient of plant profitability towards their breeding grounds (green wave hypothesis).
Kölzsch, Andrea, Nolet, B.A., Bauer, Silke, Nolet, Bart A., van der Jeugd, Henk P., Cabot, David, van der Jeugd, H., Kölzsch, A., Griffin, L., De Boer, R., Bauer, S., de Boer, Rob, Exo, K., Nolet, B., Cabot, D., Exo, Klaus-Michael, Griffin, Larry, Van der Jeugd, H.P., Exo, K-M.   +18 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Monthly eDNA Metabarcoding Data From the Coastal North Sea Area Align With Fish Species‐Specific Life Cycle Events

Environmental DNA
Coastal environments serve as essential nursing, feeding, and spawning grounds for commercially and ecologically important fish species, some of which use nearshore habitats as transitional steps in their ontogenetic migration.
Marianne Lolivier, Isolde Cornelis, Sara Maes, Jonas Mortelmans, Hans Polet, Sofie Derycke   +5 more
doaj   +1 more source

Trends, Determinants and Constraints of Temporary Sheep Migration in Rajasthan — An Economic Analysis

The study has analysed the temporary migration of sheep as a response to the demand-supply disequilibrium of fodder and water and has explored its trends, determinants and constraints by using the data collected from rural areas of semi-arid Rajasthan ...
Gupta, D.C., Suresh, A., Mann, J.S.
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Optimal migration strategies in animals that run: a range equation and its consequences

, 2003
Optimal migration theory depends to a large extent on the range equation, that is, a function relating potential distance moved to fuel load. Such range equations derived from aerodynamic principles exist for birds.
Hedenström, Anders,, Hedenström, Anders   +1 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source