Results 121 to 130 of about 1,017,023 (300)
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Wnt5a induces ROR1 to recruit cortactin to promote breast-cancer migration and metastasis. [PDF]
, 2019 ROR1 is a conserved oncoembryonic surface protein expressed in breast cancer. Here we report that ROR1 associates with cortactin in primary breast-cancer cells or in MCF7 transfected to express ROR1.
Briggs, Steven P +7 more
core +1 more source
, 2010 Aggregation of animal cells in culture comprises a series of motility, collision and adhesion processes of basic relevance for tissue engineering, bioseparations, oncology research and \textit{in vitro} drug testing.
Alves, S. G., Martins, M. L.
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Challenges and opportunities for data integration to improve estimation of migratory connectivity
Methods in Ecology and EvolutionUnderstanding migratory connectivity, or the linkage of populations between seasons, is critical for effective conservation and management of migratory wildlife.
Jeffrey A. Hostetler +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Genotype But Not Body Shape Predicts River Migration Success in Atlantic Salmon
Ecology and EvolutionMigratory species typically undertake demanding long‐distance journeys, across different habitat types during which they are exposed to multiple natural and anthropogenic stressors.
Paolo Moccetti +8 more
doaj +1 more source
Developmental stage shapes the realized energy landscape for a flight specialist
eLifeThe heterogeneity of the physical environment determines the cost of transport for animals, shaping their energy landscape. Animals respond to this energy landscape by adjusting their distribution and movement to maximize gains and reduce costs.
Elham Nourani +13 more
doaj +1 more source
Avian Song Complexity is Associated With High Field Metabolic Rate [PDF]
, 2006 Question: Is the production of bird song costly? Analyses of oxygen consumption during singing provided conflicting results. Data studied: Data on 28 passerine species with quantitative information on song complexity and field metabolic rate, which ...
Garamszegi, László Zsolt +2 more
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