Results 221 to 230 of about 27,467,558 (397)

Sustained expression of hemopexin in an animal model of sickle cell anemia. [PDF]

Blood Vessel Thromb Hemost
De Lima F, De Moraes CRP, Borba-Junior IT, Assalin HB, Abdalla Saad MJ, Costa FF, De Paula EV.   +6 more
europepmc   +1 more source

Social defeat as an animal model for depression.

ILAR journal, 2014
F. Hollis, M. Kabbaj
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model. [PDF]

Theranostics
Fadera S, Boas CAWV, Yue Y, Gu Z, Yuan J, De D, Rogers BE, Nazeri A, Chen H.   +8 more
europepmc   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Efficacy of sulfonamides targeting malic enzyme in an animal model of Chagas disease. [PDF]

Front Pharmacol
Dos Santos TCF, da Silva RB, de Sousa IL, Naciuk FF, Marchese L, Eufrásio AG, Lobo-Rojas AE, Giampauli RM, de Souza VB, Schenka AA, Bruder M, Rocco SA, Cordeiro AT.   +12 more
europepmc   +1 more source

Microdialysis detection of lactate in subcutaneous tissue as a reliable indicator of tissue metabolic disorders in an animal sepsis model

, 2011
Hitoshi Ohashi, Naruo Kawasaki, Hirotsugu Komatsu, Takafumi Wada, Akiko Hosoyama, Nobuyoshi Hanyu, Katsutoshi Kobayashi, Maiko Ohashi, Yasuhiko Taira   +8 more
openalex   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Machine learning-based prediction of drug response in ischemia reperfusion animal model. [PDF]

Sci Rep
Abd ElGwad AM, Youssef I, Khaled A, Habib EK, Omar NN, Khader HF, Alaiyed SS, Altayyar M, Aboulhoda BE, Matboli M.   +9 more
europepmc   +1 more source