Results 281 to 290 of about 26,422,673 (403)

The mechanism underlying streptozotocin injection for the development of a nontransgenic Alzheimer's disease animal model. [PDF]

Open Vet J
Titisari N, Ahmad H, Samsulrizal N, Fauzi A, Abdul Razak IS.   +4 more
europepmc   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Expression of Concern: Paroxetine treatment in an animal model of depression improves sperm quality. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Animal Models in 'Exemplary' Medical Research: Diabetes as a Case Study

, 1989
James Lindemann Nelson
openalex   +2 more sources

Model animals and their applications [PDF]

Science China Life Sciences, 2015
openaire   +3 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast cancer. [PDF]

EJNMMI Res
Weng CC, Chiang CC, Chung YH, Ho YP, Chang YC, Hsiao IT, Mach RH.   +6 more
europepmc   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Non-invasive detection of instantaneous fetal hypoxemia in large animal model of pregnancy. [PDF]

NPJ Biomed Innov
Qian W, Saffarpour M, Joarder RR, Kasap B, Vali K, Lihe T, Hedriana HL, Wang A, Farmer D, Ghiasi S.   +9 more
europepmc   +1 more source

Animal model for schizophrenia [PDF]

, 2013
Riquelme-Alacid, Gemma, Universitat Autònoma de Barcelona. Facultat de Biociències   +1 more
core