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Animal Models of Osteomyelitis
The International Journal of Artificial Organs, 2006There are numerous reports in the literature using animal models of osteomyelitis for investigating pathogenesis, diagnosis, and treatment of bone infections. Rabbits, rats, and dogs are commonly used animals, and, less frequently, chickens, guinea pigs, miniature pigs, goats, and sheep.
An Y. H. +2 more
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Exercise and Sport Sciences Reviews, 1994
Exercise adaptations induce the differential expression of genes that encode components of the contractile apparatus, metabolic pathways, organelle systems, and membrane components. These changes in gene expression are presumably brought about by the activation of intracellular signaling pathways.
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Exercise adaptations induce the differential expression of genes that encode components of the contractile apparatus, metabolic pathways, organelle systems, and membrane components. These changes in gene expression are presumably brought about by the activation of intracellular signaling pathways.
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Annals of Emergency Medicine, 1984
Bradyarrhythmias, with or without hypotension, may be associated with acute myocardial infarction, especially inferior. The early use of atropine in the management of sinus bradycardia, with associated hypotension, spurred a continuing controversy that has found only partial solution in animal models.
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Bradyarrhythmias, with or without hypotension, may be associated with acute myocardial infarction, especially inferior. The early use of atropine in the management of sinus bradycardia, with associated hypotension, spurred a continuing controversy that has found only partial solution in animal models.
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APMIS, 1996
Insulin‐dependent (type 1) diabetes is a frequent disease with an incidence of up to about 1%. It requires daily treatment and serious late complications are observed. Good animal models exist for studying diabetes. These can be categorized as animals with spontaneously developing diabetes (BB rats, NOD mice) and as animals with induced diabetes (e.g ...
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Insulin‐dependent (type 1) diabetes is a frequent disease with an incidence of up to about 1%. It requires daily treatment and serious late complications are observed. Good animal models exist for studying diabetes. These can be categorized as animals with spontaneously developing diabetes (BB rats, NOD mice) and as animals with induced diabetes (e.g ...
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CRISPR in Animals and Animal Models
2017CRISPR-Cas9 has revolutionized the generation of transgenic animals. This system has demonstrated an unprecedented efficiency, multiplexability, and ease of use, thereby reducing the time and cost required for genome editing and enabling the production of animals with more extensive genetic modifications.
Ellen, Shrock, Marc, Güell
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Current animal models: cotton rat animal model.
Current topics in microbiology and immunology, 2009The cotton rat (Sigmodon hispidus) model has proven to be a suitable small animal model for measles virus pathogenesis to fill the niche between tissue culture and studies in macaques. Similar to mice, inbred cotton rats are available in a microbiologically defined quality with an ever-increasing arsenal of reagents and methods available for the study ...
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Animal Models of Osteoarthritis
Biorheology: The Official Journal of the International Society of Biorheology, 1999Animal models have proved to be of considerable importance in elucidating mechanisms underlying joint damage in osteoarthritis (OA) and providing proof of concept in the development of pharmacologic and biologic agents that may modify structural damage in the OA joint.
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Depression: a new animal model sensitive to antidepressant treatments
Nature, 1977R. Porsolt, M. Pichon, M. Jalfre
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Modeling Depression in Animal Models
2011Animal models and preclinical tests have played large roles in the development of antidepressant drugs and are likely to continue to play important roles. In the present communication, the main animal models of depression have been described and reviewed.
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