Results 111 to 120 of about 438,882 (262)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Animal movement ecology in India: insights from 2011-2021 and prospective for the future. [PDF]

PeerJ, 2022
Prakash H, Kumar RS, Lahkar B, Sukumar R, Vanak AT, Thaker M.   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Examination of head versus body heading may help clarify the extent to which animal movement pathways are structured by environmental cues? [PDF]

Mov Ecol, 2023
Gunner RM, Wilson RP, Holton MD, Bennett NC, Alagaili AN, Bertelsen MF, Mohammed OB, Wang T, Manger PR, Ismael K, Scantlebury DM.   +10 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Affordable RFID loggers for monitoring animal movement, activity, and behaviour. [PDF]

PLoS One, 2022
Harrison ND, Kelly EL.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Editorial: Computational modeling and simulation of quadrupedal animal movement. [PDF]

Front Bioeng Biotechnol, 2022
Bertocci G, Hutchinson JR, Marcellin-Little DJ, Pandy MG.   +3 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Deriving spatially explicit direct and indirect interaction networks from animal movement data. [PDF]

Ecol Evol, 2023
Yang A, Wilber MQ, Manlove KR, Miller RS, Boughton R, Beasley J, Northrup J, VerCauteren KC, Wittemyer G, Pepin K.   +9 more
europepmc   +1 more source