Results 141 to 150 of about 5,218,704 (334)

Using time-series similarity measures to compare animal movement trajectories in ecology

open access: yesBehavioral Ecology and Sociobiology, 2019
Identifying and understanding patterns in movement data are amongst the principal aims of movement ecology. By quantifying the similarity of movement trajectories, inferences can be made about diverse processes, ranging from individual specialisation to ...
I. Cleasby   +6 more
semanticscholar   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Philosophy behind the Movement: Animal Studies versus Animal Rights

open access: yes, 2011
Recently, many pro-animal thinkers have expressed critical views on the animal rights movement. In particular, the movement has been criticized for being philosophically uninformed, politically regressive, and practically unpersuasive.
Elisa Aaltola
core   +1 more source

Signatures of chaos in animal search patterns [PDF]

open access: yes, 2016
One key objective of the emerging discipline of movement ecology is to link animal movement patternsto underlying biological processes, including those operating at the neurobiological level.
Kölzsch, Andrea   +13 more
core   +1 more source

Spatiotemporal Overlap of Mallards With Poultry Farms Is Associated With Greater Risk of Avian Influenza Wild Bird Spillover Events

open access: yesEcology and Evolution
Animal movement influences local transmission and geographic spread of pathogens. Waterfowl are known reservoirs of pathogens, including H5 goose/Guangdong lineage (H5 GsGd) highly pathogenic avian influenza (HPAI).
Joshua A. Cullen   +12 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Animal movement “on track”: reconciling the spatial and temporal nature of animal trajectories [PDF]

open access: yes, 2012
Animals do not occupy the space at random, but in dependence of distribution of resources allowing survival and reproduction. Indeed, the position of animals in space and time relate the animal to its environment; vice versa, most animals respond to ...
Gueting, R. H.   +6 more
core  

Trash Talking: Anthropogenic Resources Facilitate Raccoon Interactions in Urban Environments

open access: yesEcology and Evolution
Interactions between animals of the same species underpin many ecological processes, from reproduction to pathogen transmission. Habitat modification, such as urbanization, affects an animal's spatial behavior, altering interactions with both their ...
Laura Dudley Plimpton   +10 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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