Results 151 to 160 of about 10,496,554 (311)
Research progress in physiological effects of resistant substances of Urtica dioica L. on animal performance and feed conversion. [PDF]
Front Plant Sci, 2023 Zhang Y +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The book applies a productive interdisciplinary lens of art history, performance, and animal studies for approaching political economy issues, critiquing anthropomorphic worldviews, and provoking thoughts around animal and human nature that spark impulses for an innovative performance aesthetics and ethics.
openaire +4 more sources
Animal welfare and performance
, 2009 RESUMO - Performance e Bem-estar Animal Intensidade do cio em bovinos de leite na Suécia – Existem relações com os parâmetros de bem-estar baseados no animal? - Foi realizado um estudo de campo numa vacaria experimental de leite na Suécia para determinar a presença e relevância das relações entre parâmetros de bem-estar com base no animal e fertilidade
openaire +2 more sources
Small animal dermatology : a color atlas and therapeutic guide /
, 2011 Designed with busy practitioners and students in mind, Small Animal Dermatology: A Color Atlas and Therapeutic Guide provides concise, thorough coverage of over 250 skin diseases affecting small animals. More than 1,000 high-quality images help to ensure
Medleau, Linda.Small animal dermatology. +1 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Does Replacing Maize with Barley Affect the Animal Performance and Rumen Fermentation, including Methane Production, of Beef Cattle Fed High-Concentrate Diets On-Farm? [PDF]
Animals (Basel), 2023 Arbaoui A, de Vega A.
europepmc +1 more source