Results 151 to 160 of about 553,501 (299)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Editorial: Chloride homeostasis in animal cell physiology

open access: yesFrontiers in Physiology, 2023
Jinwei Zhang   +6 more
doaj   +1 more source

BIOL 450 Animal Physiology

open access: yes, 1987
Course syllabus for BIOL 450 Animal Physiology Course description: This course emphasizes general physiological principles by examining the cell and organ physiology of major body systems including the nervous, musculo-skeletal, cardiovascular, immune ...
Klingensmith, Phyllis M.
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Integrative Physiology: At the Crossroads of Nutrition, Microbiota, Animal Physiology, and Human Health. [PDF]

open access: yesCell Metab, 2017
Leulier F   +7 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

A comparison of hatchery-rearing in exercise to wild animal physiology and reflex behavior in Aplysia californica. [PDF]

open access: yesComp Biochem Physiol A Mol Integr Physiol, 2018
Fieber LA   +7 more
europepmc   +1 more source

Journal of animal physiology and animal nutrition.

open access: yes
Voortzetting van: Zeitschrift fur Tierphysiologie, Tierernahrung und Futtermittelkunde = Journal of animal physiology and animal ...

core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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