Results 171 to 180 of about 8,788,549 (250)

Addressing challenges and leveraging opportunities for capacity building and the sustainable development of animal production in the south. [PDF]

Anim Front
Attia YA, Asiry KA, Nagadi SA, Khafaga AF, Alhotan RA, Calabrò S, Koura BI, Shafi ME, Alyileili SR, Galal A, Aggrey SE, Rekaya R.   +11 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

A cost-effective method for combining the power of genetic and epigenetic selection in animal production. [PDF]

Environ Epigenet
Sánchez-Baizán N, Herlin M, Millán A, Martínez P, López Belluga MD, Piferrer F.   +5 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Sustainability of Animal Production Chains: Alternative Protein Sources as an Ecological Driver in Animal Feeding: A Review. [PDF]

Animals (Basel)
Lanza M, Battelli M, Gallo L, Soglia F, Bovera F, Giunta F, Primi R, Biondi L, Giannuzzi D, Zampiga M, Addeo NF, Cannas A, Danieli PP, Ronchi B, Crovetto GM.   +14 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

ASAS-NANP symposium: mathematical modeling in animal nutrition: contributions of mathematical modeling to life cycle assessment to support environmental sustainability of animal production. [PDF]

J Anim Sci
Cadéro A, Tedeschi LO, Garcia-Launay F.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Estimating air emissions from animal production in the United States using statistical models: Ammonia emissions from swine grow-finish barns. [PDF]

Atmos Environ X
Rumsey IC, Nash MN, Walker JT.
europepmc   +1 more source