Results 221 to 230 of about 5,413,831 (314)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

The effects of irradiation on the development of Theileria parva sporozoites [PDF]

open access: yes, 2012
International Laboratory for Research on Animal Diseases
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Human nutritional status as a measure of the impact of livestock disease control [PDF]

open access: yes, 2012
International Laboratory for Research on Animal Diseases
core  

Noise as an Extrinsic Variable in the Animal Research Facility. [PDF]

open access: yesJ Am Assoc Lab Anim Sci
Turner JG, Manker JR.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Assessing the impact of better control of livestock diseases in Africa [PDF]

open access: yes, 2012
International Laboratory for Research on Animal Diseases
core  

Non-verbal effecting - animal research sheds light on human emotion communication. [PDF]

open access: yesBiol Rev Camb Philos Soc
Schirmer A   +3 more
europepmc   +1 more source

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