Results 91 to 100 of about 9,809,915 (420)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

A new era for the Journal of Animal Science and Technology

open access: yesJournal of Animal Science and Technology, 2014
We anticipate that this new alliance between The Korean Society of Animal Science and Technology and BioMed Central will elevate our journal one step higher, and facilitate easier access for those overseas as well as domestic researchers, who in turn ...
I. Choi
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Principles of Mathematical Modeling Applied to Animal

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
One of the characteristics by which we can estimate the stage of development of a certain discipline is its degree of mathematization. Thus, Galileo Galilei said that „The great book of nature can be read only by the one who knows the language in which ...
Cosmin Nitu, Radu Burlacu, Livia David
doaj  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Editorial: Buffalo Health and Production

open access: yesFrontiers in Veterinary Science, 2022
Antonio Humberto Hamad Minervino   +3 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Introduction to computer animation and its possible educational applications [PDF]

open access: yesNew Challenges in Education. Retrospection of history of education to the future in the interdisciplinary dialogue among didactics of various school subjects. Catholic University in Ruzomberok, Slovakia: VERBUM, pp.177-205, 2013, 2013
Animation, which is basically a form of pictorial presentation, has become the most prominent feature of technology-based learning environments. It refers to simulated motion pictures showing movement of drawn objects. Recently, educational computer animation has turned out to be one of the most elegant tools for presenting multimedia materials for ...
arxiv  

Identifying animal species in camera trap images using deep learning and citizen science

open access: yesMethods in Ecology and Evolution, 2018
Ecologists often study wildlife populations by deploying camera traps. Large datasets are generated using this approach which can be difficult for research teams to manually evaluate.
M. Willi   +7 more
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

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