Results 41 to 50 of about 1,502,357 (309)
Population Ecology, EarlyView.Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi +3 more
wiley +1 more source
Automatic imitation of intransitive actions in macaws
iScienceSummary: Automatic imitation is the involuntary tendency of humans to copy others’ actions even when counterproductive. We examined the automatic imitation of intransitive actions in blue-throated macaws (Ara glaucogularis), employing a stimulus-response-
Esha Haldar +2 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Laboratory Animal Welfare Approach in Science
Southeastern European Medical Journal, 2020 The term laboratory animal welfare has been generating a huge amount of controversial questions in science since the very beginning. Humans use animals that are suited to their needs, be they of a psychosocial, therapeutic, official, scientific or ...
Iris Broman
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Why has animal science not led to improved farm animal health and welfare?
Frontiers in Animal ScienceTo sustain the economic viability of a livestock farm in a global market, characterised by a price undercutting competition, farmers are forced to adapt to what the market demands.
Albert Sundrum
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Principles of Mathematical Modeling Applied to Animal
Scientific Papers Animal Science and Biotechnologies, 2023 One of the characteristics by which we can estimate the stage of development of a certain discipline is its degree of mathematization. Thus, Galileo Galilei said that „The great book of nature can be read only by the one who knows the language in which ...
Cosmin Nitu, Radu Burlacu, Livia David
doaj
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Animals, 2015 Metabolic disorders are a key problem in the transition period of dairy cows and often appear before the onset of further health problems. They mainly derive from difficulties the animals have in adapting to changes and disturbances occurring both ...
Albert Sundrum
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FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source