Results 111 to 120 of about 12,756,330 (201)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
, 2023 This internet resource contains issues published throughout multiple years2023 Livestock Brand Renewal Window is Currently Open! -- New: Free Electronic CVI Available for Veterinarians -- Statewide FMD Exercise -- USDA Seeks Public Comment on Proposal to
Kansas Animal Health
core
Cutting-Edge Topics in Research on Veterinary Sciences
SVU-International Journal of Veterinary Sciences, 2018 We are pleased to announce the first edition of the SVU-International Journal of Veterinary Sciences (SVU-IJVS). We hope that this journal will advance the field of animal sciences and related biomedical disciplines.
Seddik Hammad +2 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Sociologies, 2017 Animal intentionality or agentivity are today frequently considered in the social sciences as derived from human intentionality. This idea has different versions. Humans would have intentionally shaped domestic animals.
Dominique Guillo
doaj
Automatic imitation of intransitive actions in macaws
iScienceSummary: Automatic imitation is the involuntary tendency of humans to copy others’ actions even when counterproductive. We examined the automatic imitation of intransitive actions in blue-throated macaws (Ara glaucogularis), employing a stimulus-response-
Esha Haldar +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source