Results 1 to 10 of about 553,501 (299)

MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes

open access: yesiScience, 2022
Summary: MYCT1 has been shown to function as a tumor suppressor in various tumors, but its role in metabolism has never been reported. Here, we showed that global inactivation of Myct1 in mice led to progressive accumulation of glycogen in the liver ...
Dong-Xue Ding   +3 more
doaj   +1 more source

Oxygen-carrying sequential preservation mitigates liver grafts ischemia-reperfusion injury

open access: yesiScience, 2023
Summary: Oxygen-dependent preservation has been proposed to protect liver grafts from ischemia-reperfusion injury (IRI), but its underlying mechanism remains elusive.
Jianbo Li   +7 more
doaj   +1 more source

Peptides for Skin Protection and Healing in Amphibians

open access: yesMolecules, 2019
Amphibian skin is not to be considered a mere tegument; it has a multitude of functions related to respiration, osmoregulation, and thermoregulation, thus allowing the individuals to survive and thrive in the terrestrial environment.
Ilaria Demori   +11 more
doaj   +1 more source

The genome of the naturally evolved obesity-prone Ossabaw miniature pig

open access: yesiScience, 2021
Summary: The feral pigs of Ossabaw Island (USA) have an outstanding propensity to obesity and develop complete metabolic syndrome (MetS) upon prolonged high energy dieting. We now report the first high quality genome of the Ossabaw pig with Contig N50 of
Yaolei Zhang   +5 more
doaj   +1 more source

The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney

open access: yesiScience, 2023
Summary: The zebrafish is a unique model to understand hematopoietic niches as hematopoietic stem/progenitor cells are maintained in the kidney. However, little is known about which cell types in the kidney play a role in hematopoietic niches.
Mao Kondo   +6 more
doaj   +1 more source

Celecoxib alleviates pathological cardiac hypertrophy and fibrosis via M1-like macrophage infiltration in neonatal mice

open access: yesiScience, 2021
Summary: Cardiac hypertrophy is an adaptive response to all forms of heart disease, including hypertension, myocardial infarction, and cardiomyopathy. Cyclooxygenase-2 (COX-2) overexpression results in inflammatory response, cardiac cell apoptosis, and ...
Yanli Zhao   +6 more
doaj   +1 more source

The effectiveness of animal physiology practical book based on guided inquiry model

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia), 2019
The effectiveness of animal physiology practical book based on guided inquiry model is the essential factor to achievement student understanding a about animal physiology concepts.
Rina Widiana   +3 more
doaj   +1 more source

C24:0 avoids cold exposure-induced oxidative stress and fatty acid β-oxidation damage

open access: yesiScience, 2021
Summary: Low temperatures can cause severe growth inhibition and mortality in fish. Previous studies about the cold resistance of fish mainly focused on the role of unsaturated fatty acids, rather than saturated fatty acids (SFAs).
Shouxiang Sun, Xiaojuan Cao, Jian Gao
doaj   +1 more source

Effects of carbamazepine on the central nervous system of zebrafish at human therapeutic plasma levels

open access: yesiScience, 2023
Summary: The fish plasma model (FPM) facilitated the environmental risk assessment of human drugs by using existing data on human therapeutic plasma concentrations (HTPCs) and predicted fish plasma concentrations (FPCs). However, studies on carbamazepine
Weiwei Yang   +5 more
doaj   +1 more source

Urine cortisol in pigs of different MH-genotypes

open access: yesActa Agriculturae Slovenica, 2003
Urine cortisol concentration was evaluated in German Landrace barrows of two MH-genotypes (NN, Nn) housed in metabolic cages. Furthermore, cortisol in urine was evaluated as a substitute measure of plasma cortisol values in pigs.
Nataša SIARD   +3 more
doaj   +1 more source

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