Results 41 to 50 of about 553,501 (299)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Effect of vitamin-mineral premix on some relationships between serum parameters in breeding horses

open access: yesActa Agriculturae Slovenica, 2003
Eight Arabian stallions were selected from clinically normal horses. After 10 day adaptation period the animals were divided into two equal groups: control and experimental. All horses were housed individually and allowed to walk on sandy paddock twice a
Mansur S. HAREADY
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Editorial: Rising stars in aquatic physiology: 2022 [PDF]

open access: yes, 2022
Promoting and visualizing cutting-edge research from young generations is the cornerstone of our academic environment. Under this scenario, this Research Topic aims gathering innovative research studies on aquatic physiology, studies that range from ...
Gisbert, E.   +6 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Post-Exercise Shifts in the Hemato–Biochemical Profile of Unacclimatized Camels (Camelus dromedarius)

open access: yesAnimals
Exercise-unacclimatized dromedary camels regularly perform strenuous work in desert heat; however, their short-term hematologic and biochemical recovery is not well defined.
Mohammed A. Al-Badwi   +3 more
doaj   +1 more source

Bacterial lipopolysaccharides can initiate regeneration of the Xenopus tadpole tail

open access: yesiScience, 2021
Summary: Tadpoles of the frog Xenopus laevis can regenerate tails except for a short “refractory” period in which they heal rather than regenerate. Rapid and sustained production of ROS by NADPH oxidase (Nox) is critical for regeneration.
Thomas F. Bishop, Caroline W. Beck
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy