Results 61 to 70 of about 1,128,692 (290)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bacterial lipopolysaccharides can initiate regeneration of the Xenopus tadpole tail

open access: yesiScience, 2021
Summary: Tadpoles of the frog Xenopus laevis can regenerate tails except for a short “refractory” period in which they heal rather than regenerate. Rapid and sustained production of ROS by NADPH oxidase (Nox) is critical for regeneration.
Thomas F. Bishop, Caroline W. Beck
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity [PDF]

open access: yes, 2016
Animals, especially ectotherms, are highly sensitive to the temperature of their surrounding environment. Extremely high temperature, for example, induces a decline of average performance of conspecifics within a population, but individual heterogeneity ...
Anderson, Graeme J.   +4 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Book Review: Insect Physiology and Biochemistry. Second Edition. CRC Press, Boca Raton. [PDF]

open access: yes, 2008
Insect physiology is a specialized discipline within the larger framework of animal physiology. Almost every graduate program in Entomology has a requirement for an insect physiology course and an up to date textbook is required.
Jurenka, Russell, Jurenka, Russell
core   +1 more source

Effects of maternal subnutrition during early pregnancy on cow hematological profiles and offspring physiology and vitality in two beef breeds [PDF]

open access: yes, 2019
This experiment evaluated the effects of subnutrition during early gestation on hematology in cows (Bos Taurus) and on hematological, metabolic, endocrine, and vitality parameters in their calves.
Almaguer C.   +9 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Developing and validating the ACCA (Activation-Collaboration-Creation-Application) learning model to enhance students’ collaboration

open access: yesResearch and Development in Education
Collaboration skills are crucial for students to engage in teamwork, solve problems collectively, and construct deeper understanding through interactive discussions.
Andi Muharni   +4 more
doaj   +1 more source

Theories of the development of human communication [PDF]

open access: yes, 2013
This article considers evidence for innate motives for sharing rituals and symbols from animal semiotics, developmental neurobiology, physiology of prospective motor control, affective neuroscience and infant communication. Mastery of speech and language
Delafield-Butt, Jonathan   +1 more
core  

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