Results 81 to 90 of about 553,501 (299)
Regulation of interstitial fluid flow in adventitia along vasculature by heartbeat and respiration
iScienceSummary: Converging studies showed interstitial fluid (ISF) adjacent to blood vessels flows in adventitia along vasculature into heart and lungs. We aim to reveal circulatory pathways and regulatory mechanism of such adventitial ISF flow in rat model. By
Hongyi Li +21 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Ocean warming drives tissue-wide metabolic reprogramming in a fish
iScienceSummary: Ocean warming and marine heatwaves are predicted to have adverse impacts on marine organisms. Yet, knowledge of the molecular mechanisms that underpin successful or failed acclimation to increasing temperatures remains incomplete.
Billy Moore +4 more
doaj +1 more source
, 1969 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Weickhardt, Leonard W.
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
F1000Research, 2014 Previous research identified a locus on Chromosome 14 as an important regulator of endurance exercise capacity in mice. The aim of this study was to investigate the effect of chromosome substitution on intrinsic exercise capacity and identify ...
Sean M. Courtney, Michael P. Massett
doaj +1 more source
BIOL 450/451 Animal Physiology/Animal Physiology Laboratory
, 1998 Course syllabus for BIOL 450/451 Animal Physiology/Animal Physiology Laboratory Course description: The lecture course emphasizes physiological principles of mammalian physiology by examining the cell and organ physiology of the nervous, muscular, blood,
Klingensmith, Phyllis M.
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Student perceptions of the impact of quality matters essential standards in an animal physiology course. [PDF]
Transl Anim Sci, 2023 Deuser K +5 more
europepmc +1 more source