Results 71 to 80 of about 553,501 (299)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Animal reproduction and physiology/Reproducción y Fisiología/Reprodução e Fisiologia
, 2018 Animal reproduction and physiology/Reproducción y Fisiología/Reprodução e ...
Editor, Managing
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Development of Professional Skills through Subject Animal Anatomophysiology
Agrisost, 2019 Context: One of the most important problems of pedagogical work in higher education is the process of professional skills training, which is part of professional education, in which scientific information should be applied in a creative manner to provide
Humberto B. Sóñora Revoredo +4 more
doaj
Regulatory processes in the control of cholestrol synthesis in rat liver / by M.J. James [PDF]
, 1976 73 leaves : ill., tables ; 30 cm.Thesis (Ph.D.) -- University of Adelaide, Dept.
James, Michael John
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Major in Animal Physiology with a Specialization in Ethology
, 2009 Concern about the well-being of domesticated animals has increased dramatically in the United States and across many other industrialized countries. The issues involved are complex, and there is widespread disagreement both as to the extent of human
Johnson, Anna
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Leonardo da Vinci's Animal Anatomy: Bear and Horse Drawings Revisited [PDF]
, 2019 Leonardo da Vinci was one of the most influencing personalities of his time, the perfect representation of the ideal Renaissance man, an expert painter, engineer and anatomist.
Lombardero Fernández, Matilde +3 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source