Results 31 to 40 of about 547,491 (249)

A Neuro-Symbolic Bioinformatics Framework for Unlocking Chordate Physiological Dark Data and Validating Allometric Scaling

open access: yesBiology
Animal functional trait data are essential for macroecology, but massive datasets remain locked in unstructured scientific literature. Traditional manual extraction is inefficient, and general-purpose artificial intelligence (AI) systems struggle with ...
Zhiyao Duan   +3 more
doaj   +1 more source

Simplified drug efficacy screening system for sleep-disorder drugs using non-human primates

open access: yesHeliyon, 2020
The most widely used animal models to develop sleep-disorder drugs are rodents, particularly rats and mice. However, unlike humans, these rodents are nocturnal.
Keita Sakai   +5 more
doaj   +1 more source

Depletion of cardiac cardiolipin synthase alters systolic and diastolic function

open access: yesiScience, 2021
Summary: Cardiolipin (CL) is a major cardiac mitochondrial phospholipid maintaining regular mitochondrial morphology and function in cardiomyocytes. Cardiac CL production includes its biosynthesis and a CL remodeling process.
Elia Smeir   +13 more
doaj   +1 more source

TPACK Capability Analysis Students of Biology Education Study Program on Animal Physiology Learning with Online Learning Models

open access: yesJournal of Innovative Science Education, 2023
The aim of education in Indonesia is to educate the life of the nation. In an effort to realize the goals of Indonesian education, a teacher as an educator must understand and have Technological Pedagogical Content Knowledge (TPACK) skills, especially ...
Diana Putri Ristianafi   +2 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Effect of sweet chestnut extract (Farmatan®) on the digestibility and bioavailability of nitrogen and some minerals in the laboratory rats

open access: yesActa Agriculturae Slovenica, 2016
Study was conducted to investigate the dietary effect of hydrolysable tannin from sweet chestnut on the protein digestibility and bioavailability, dry matter and organic matter apparent digestibility and apparent digestibility and apparent ...
Tatjana PIRMAN, Andrej OREŠNIK
doaj   +1 more source

Temporal metabolic and transcriptomic characteristics crossing islets and liver reveal dynamic pathophysiology in diet-induced diabetes

open access: yesiScience, 2021
Summary: To investigate the molecular mechanisms underlying islet dysfunction and insulin resistance in diet-induced diabetes, we conducted temporal RNA sequencing of tissues responsible for insulin secretion (islets) and action (liver) every 4 weeks in ...
Rui Gao   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Effect of vitamin-mineral premix on some relationships between serum parameters in breeding horses

open access: yesActa Agriculturae Slovenica, 2003
Eight Arabian stallions were selected from clinically normal horses. After 10 day adaptation period the animals were divided into two equal groups: control and experimental. All horses were housed individually and allowed to walk on sandy paddock twice a
Mansur S. HAREADY
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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