Results 71 to 80 of about 7,407,230 (297)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Manipulating Particle Size to Impact Animal Performance
, 2014 Fahrenholz, Adam. (2014). Manipulating Particle Size to Impact Animal Performance.
Fahrenholz, Adam
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, 2011 [EN] The aim of this work was to evaluate the response to 10 generations of selection for ovulation rate. Selection was based on the phenotypic value of ovulation rate, estimated at d 12 of the second gestation by laparoscopy.
Laborda Vidal, Patricia +7 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Determinants of Work Animal Density in Tamil Nadu: An Econometric Analysis [PDF]
From independence, size and composition of bovines in Tamil Nadu showed differential growth pattern. The total bovine population showed an increasing trend up to the early-Sixties and thereafter stagnant till the early Eighties.
Dhas, Albert Christopher
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Inoculum size for experimental animal models for Chagas disease.
, 2015 a trypomastigotes/animalInoculum size for experimental animal models for Chagas disease.
Julián Ernesto Nicolás Gulin (828986) +2 more
core +1 more source
FARM STRUCTURE IN ANIMAL SECTOR OF ROMANIA [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2021 The paper aimed to analyze the number of animal holdings, their structure by species and size class and also the average farm size based on the data provided by Eurostat and National Institute of Statistics.
Agatha POPESCU +1 more
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Size distribution of airborne particles in animal houses [PDF]
, 2014 The concentration and size distribution of airborne particles were measured inside and outside typical animal houses such as broilers, broiler breeders (both floor housing with litter); layers (floor housing system and aviary housing system); turkeys ...
Lai, T.L.H. +8 more
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