Results 101 to 110 of about 16,257,748 (254)
The Power of the Dog: Caesar of Notts and the Mourning of Edward VII
Royal Studies Journal, 2023 Like his mother Queen Victoria, Edward VII kept a thriving kennel at Sandringham and developed close bonds with several of his dogs. His most well-known canine companion was Caesar of Notts, a wirehaired fox terrier who entered the royal kennels in 1903.
Terri Sabatos
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Critical animal law studies have evolved as a subfield of animal law scholarship to compliment the mainstream liberal approaches including animal welfarism and animal rights.
Offor, Iyan
core +3 more sources
Słoń a sprawa literaturoznawców, czyli o zoofilologii słów kilka. Rekonesans
Zoophilologica, 2015 This article is entirely dedicated to zoophilology—a new discipline of research, which emerged with the fusion of philological sciences and modern, ethically deepened animal studies.
Piotr Krupiński
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Kansas Pet Animal Act: Policy and Procedures Field Manual, 2009
, 2009 January 1, 2009The Kansas Pet Animal Act requires licensing and inspection of all dog and cat breeders who produce, offer or sell three or more litters during the state fiscal year, pounds and shelters, pet shops, research facilities, distributors, out ...
Kansas Animal Health.
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source