Results 81 to 90 of about 16,257,748 (254)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Feminist Animal and Multispecies Studies : Critical Perspectives on Food and Eating
This book develops critical feminist animal and multispecies studies across various societal and environmental contexts. The chapters discuss timely questions broadly related to food and eating, stemming from connections drawn between critical animal ...
Irni, Kuura
core +1 more source
Analyzing Categories: Harvey Sacks and Critical Animal Studies [PDF]
, 2014 This paper is a development of my argument for animal queer and aims to conduct an analysis of some critical animal studies issues in queer terms. In order to do so it pursues queer’s definitional concern with categories through Harvey Sacks’s concept of
DELL'AVERSANO, CARMEN
core
2i Revista de Estudos de Identidade e Intermedialidade, 2023 Este artigo propõe uma análise sobre os animais nos relatos de viagem, escritos no contexto da colonização portuguesa na América durante o século XVIII, a partir da teoria das multiplicidades de Deleuze e Guattari.
Maria Eduarda Góes Barboza da Silva +2 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Regional issues on animal genetic resources: trends, policies and networking in Europe [PDF]
, 2010 European countries are individually and in collaboration carrying out active work on animal genetic resources (AnGR). The region has a very good starting point for work on AnGR: The breed concept was developed in Europe; current European mainstream ...
A. Mäki-Tanila +5 more
core +1 more source
Humanities, 2016 The othering of whole groups of people in a biopolitical discourse during the Third Reich has caused many to re-assess ethics that is based on specific categories.
Belinda Kleinhans
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source