Results 71 to 80 of about 16,257,748 (254)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Animal rights & human identity: a polemical quest for authenticity [PDF]

open access: yes, 2000
This thesis examines the hypothesis that The conflict between animal advocates and animal users is far more than a matter of contrasting tastes or interests.
O'Neill, Pamela Susan   +1 more
core  

Nation of Mechanics: Automobility, Animality, and Indigeneity in John Joseph Mathews’s Sundown (1934)

open access: yesEuropean Journal of American Studies
In the early twentieth century, American national identity became increasingly associated with automobility and the move from “a nation of horsemen to a nation of mechanics,” as automotive periodical Horseless Age described it.
Daniel Bowman
doaj   +1 more source

But Is It Sociology?

open access: yesEngaging Science, Technology, and Society, 2016
This essay explores issues of trandisciplinarity through an autobiographical lens. Specifically, the essay attends to tensions between the discipline of sociology and interdisciplinary science, knowledge, and technology studies, with an emphasis on ...
Monica J. Casper
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Animal Health News

open access: yes, 2023
This internet resource contains issues published throughout multiple years2023 Livestock Brand Renewal Window is Currently Open! -- New: Free Electronic CVI Available for Veterinarians -- Statewide FMD Exercise -- USDA Seeks Public Comment on Proposal to
Kansas Animal Health
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Reviewing Existing Knowledge Prior to Conducting Animal Studies [PDF]

open access: yes, 2008
Highly polarised viewpoints about animal experimentation have often prevented agreement. However, important common ground between advocates and opponents was demonstrated within a discussion forum hosted at www.research-methodology.org.uk in July–August ...
Knight, Andrew
core  

Contribution of genetics to the study of animal personalities: a review of case studies [PDF]

open access: yes, 2005
The need for evolutionary studies on quantitative traits that integrate genetics is increasing. Studies on consistent individual differences in behavioural traits provide a good opportunity to do controlled experiments on the genetic mechanisms ...
de Jong, G.   +13 more
core   +2 more sources

Home - About - Disclaimer - Privacy