Results 71 to 80 of about 16,257,748 (254)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Animal rights & human identity: a polemical quest for authenticity [PDF]
This thesis examines the hypothesis that The conflict between animal advocates and animal users is far more than a matter of contrasting tastes or interests.
O'Neill, Pamela Susan +1 more
core
In the early twentieth century, American national identity became increasingly associated with automobility and the move from “a nation of horsemen to a nation of mechanics,” as automotive periodical Horseless Age described it.
Daniel Bowman
doaj +1 more source
This essay explores issues of trandisciplinarity through an autobiographical lens. Specifically, the essay attends to tensions between the discipline of sociology and interdisciplinary science, knowledge, and technology studies, with an emphasis on ...
Monica J. Casper
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
This internet resource contains issues published throughout multiple years2023 Livestock Brand Renewal Window is Currently Open! -- New: Free Electronic CVI Available for Veterinarians -- Statewide FMD Exercise -- USDA Seeks Public Comment on Proposal to
Kansas Animal Health
core
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Reviewing Existing Knowledge Prior to Conducting Animal Studies [PDF]
Highly polarised viewpoints about animal experimentation have often prevented agreement. However, important common ground between advocates and opponents was demonstrated within a discussion forum hosted at www.research-methodology.org.uk in July–August ...
Knight, Andrew
core
Contribution of genetics to the study of animal personalities: a review of case studies [PDF]
The need for evolutionary studies on quantitative traits that integrate genetics is increasing. Studies on consistent individual differences in behavioural traits provide a good opportunity to do controlled experiments on the genetic mechanisms ...
de Jong, G. +13 more
core +2 more sources

