Results 211 to 220 of about 643,393 (307)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Social Status Shapes Maternal Style Toward Rhesus Macaque Infants in the First Year of Life. [PDF]

Dev Psychobiol
Pilgeram NR, Kovacs-Balint ZA, Alvarado M, Jonesteller T, Sanchez MM, Bachevalier J.   +5 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Review Of Aesop\u27s Fables In Latin: Ancient Wit And Wisdom From The Animal Kingdom By L. Gibbs [PDF]

, 2009
Lefkowitz, Jeremy B.
core   +2 more sources

Unveiling Arrhythmogenic Cardiomyopathy Masquerading as Myocarditis in a Professional Athlete. [PDF]

JACC Case Rep
Garba DL, Burka S, Bavishi A, Barouch LA, Martinez MW, Kanwal AS.   +5 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Description of a collaborative sperm whale birth and shifts in coda vocal styles during key events. [PDF]

Sci Rep
Aluma Y, Baron Z, Barrett R, Baumgartner C, Beguš G, Bhattacharya S, Bronstein MM, Dahan S, Davis O, de Haas S, Defoe J, DelPreto J, Dessi R, Diamant R, Gatesy J, George K, Gero S, Gibbons D, Gibbons D, Gil S, Goldwasser S, Gruber DF, Harve O, Hernandez A, Ishay M, Jadhav N, Kc L, Kenny A, Leitao A, Lucas M, Maalouf A, Malkin P, Mevorach Y, Pagani S, Paradise O, Petri G, Poetto S, Rossi E, Rus D, Salino-Hugg M, Santoro A, Sharma P, Tchernov D, Torralba A, Tønnesen P, Vogt DM, Wood RJ.   +46 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Daily Text-Message Retrieval Practice for Pediatric Residents. [PDF]

Cureus
Nelson A, Broder M, Schwartz A, Thomas C, Abramson E.   +4 more
europepmc   +1 more source