Results 91 to 100 of about 809,866 (309)

Physical and chemical characterizations of a reference e-cigarette used in animal testing. [PDF]

Sci Rep, 2023
Soulet S, Constans L, Quinty V.
europepmc   +1 more source

Animal tests inescapable [PDF]

Nature, 2008
openaire   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Author Correction: Physical and chemical characterizations of a reference e-cigarette used in animal testing. [PDF]

Sci Rep, 2023
Soulet S, Constans L, Quinty V.
europepmc   +1 more source

Why are Validated Alternatives Not Being used to Replace Animal Tests? [PDF]

, 2018
Michael Balls
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Cytotoxicity assay as a potential alternative method for animal testing for batch release of Italian fish autogeneous vaccines. [PDF]

Open Vet J, 2023
Di Paolo A, Anzalone L, Pellegrini M, Severi G, Cagiola M.   +4 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Brain organoids and organoid intelligence from ethical, legal, and social points of view

Frontiers in Artificial Intelligence
Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain.
Thomas Hartung, Thomas Hartung, Itzy E. Morales Pantoja, Lena Smirnova   +3 more
doaj   +1 more source

Bioreactor analyses of tissue ingrowth, ongrowth and remodelling around implants: An alternative to live animal testing. [PDF]

Front Bioeng Biotechnol, 2023
Kohli N, Theodoridis K, Hall TAG, Sanz-Pena I, Gaboriau DCA, van Arkel RJ.   +5 more
europepmc   +1 more source