Results 101 to 110 of about 809,866 (309)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Analysis of RASFF notifications for mycotoxins in 2020–2022

Ветеринария сегодня
Introduction. Mycotoxins are secondary metabolites of various fungi. The contamination with mycotoxins is subject to control. Pursuant to the accepted classification in accordance with Council Directive 96/23/EC they belong to group B3: “Other substances
S. S. Ibragimova, O. V. Pruntova, N. B. Shadrova, T. V. Zhbanova   +3 more
doaj   +1 more source

Analysis of available animal testing data to propose peer-derived quantitative thresholds for determining adequate surveillance capacity for rabies. [PDF]

Sci Rep, 2023
Minhaj FS, Bonaparte SC, Boutelle C, Wallace RM.   +3 more
europepmc   +1 more source

The effects of cutting parameters on cutting forces and heat generation when drilling animal bone and biomechanical test materials

, 2017
Akos Cseke, Robert Heinemann
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Continuous Implant Load Monitoring to Assess Bone Healing Status-Evidence from Animal Testing. [PDF]

Medicina (Kaunas), 2022
Windolf M, Varjas V, Gehweiler D, Schwyn R, Arens D, Constant C, Zeiter S, Richards RG, Ernst M.   +8 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Mechanisms of altitude-driven mycotoxin variation in stored wheat: a metabolomic and transcriptomic approach

BMC Microbiology
The Alternaria fungus represents a significant threat to grain storage safety due to its production of mycotoxins, which pose serious risks to human health.
Na Wei, Jifeng Pu
doaj   +1 more source

Microglia-containing neural organoids as brain microphysiological systems for long-term culture

Frontiers in Cellular Neuroscience
Microglia, essential for brain development, homeostasis, and neuroinflammation, originate from the yolk sac during embryogenesis and migrate into the developing brain.
Alex Rittenhouse, Caroline Krall, Caroline Krall, Jesse Plotkin, Dowlette-Mary Alam El Din, Breanne Kincaid, Jason Laird, Lena Smirnova   +7 more
doaj   +1 more source

Multiparametric Material Functionality of Microtissue-Based In Vitro Models as Alternatives to Animal Testing. [PDF]

Adv Sci (Weinh), 2022
Stengelin E, Thiele J, Seiffert S.
europepmc   +1 more source