Results 131 to 140 of about 1,698,103 (349)
Multiparametric Material Functionality of Microtissue-Based In Vitro Models as Alternatives to Animal Testing. [PDF]
Adv Sci (Weinh), 2022 Stengelin E, Thiele J, Seiffert S.
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Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi. [PDF]
Arch Toxicol, 2022 Caloni F, De Angelis I, Hartung T.
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Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
, 2015 We apply methods for estimating the algorithmic complexity of sequences to behavioural sequences of three landmark studies of animal behavior each of increasing sophistication, including foraging communication by ants, flight patterns of fruit flies, and
Marshall, James A. R. +2 more
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STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity. [PDF]
Environ Health Perspect, 2022 Borba JVB +13 more
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Use of Immunofluorescence and Animal Tests to Detect Growth and Toxin Production by Clostridium botulinum Type E in Food [PDF]
, 1968 T. F. Midura +4 more
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Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
, 2010 Aggregation of animal cells in culture comprises a series of motility, collision and adhesion processes of basic relevance for tissue engineering, bioseparations, oncology research and \textit{in vitro} drug testing.
Alves, S. G., Martins, M. L.
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